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Search Results for " glutamate transporter "

12

Compounds

Cat No. Product Name Synonyms Targets
T9347 EAAT2 activator 1 3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine transporter
EAAT2 activator 1 (3-[(2-Chloro-6-fluorobenzyl)thio]-6-pyridin-2-ylpyridazine) is a thiopyridazine derivative that has been found to increase EAAT2 protein levels in astrocytes.
T2556 Nandrolone decanoate 19-Nortestosterone decanoate Others , HIV Protease
Nandrolone decanoate (19-Nortestosterone decanoate) is the decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrolone enter...
T15728 LDN-212320 LDN-0212320,LDN/OSU-0212320,OSU-0212320 transporter
LDN-212320 (OSU-0212320) is a glutamate transporter EAAT2 activator. It also enhances EAAT2 levels by > 6 fold at concentrations < 5 μM after 24 h.
T0313 Evans blue Direct Blue 53,C.I. 23860 GluR
Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).
T11451 GPI-1046 Others , HIV Protease
GPI-1046 is an immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core.
T5523 Imidazole ketone erastin IKE Ferroptosis
Imidazole ketone erastin (IKE) is an iron death inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and l...
T64357 FA16 FA 16,FA-16 Ferroptosis
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system...
T23454 TFB-TBOA Others
glial glutamate transporter EAAT1 and EAAT2 inhibitor
T12099 MPDC Others
MPDC acts as a competitive inhibitor against the Na+-dependent high-affinity glutamate transporter within forebrain synaptosomes.
T11055 DL-TBOA transporter
DL-TBOA inhibited [14C] glutamate uptake in COS-1 cells expressing human EAAT1 and EAAT2, with Ki values of 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner, with Ki values of 4.4 μM...
T35994 Erastin2 Erastin2
Erastin2 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.[1] [2] It inhibits glutamate release in CCF-STTG1 cells (IC50 = 0.0035 µM).[2] It induces cell death in HAP1 cells...
T39510 DL-TBOA ammonium
DL-TBOA ammonium is a potent, non-transportable inhibitor of excitatory amino acid transporters. Its inhibitory effects are demonstrated by IC50 values of 70 μM, 6 μM, and 6 μM for excitatory amino acid transporter-1 (EA...
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